Core requirements for influenza immunization will remain the same for
the 2017-’ 18 flu season, under a recommendation approved by a Centers
for Disease Control and Prevention
(CDC) committee June 21.
The Advisory Committee on Immunization Practices (ACIP) also recommended allowing any licensed, recommended and age-appropriate trivalent
or quadrivalent inactivated influenza
vaccine (IIV) or recombinant influenza vaccine (RIV) for pregnant women.
The previous recommendation specified use of IIV for pregnant women.
In addition, the committee reiterated that the quadrivalent live attenuated influenza vaccine (LAIV4), which
is given by nasal spray, not be used in
any setting during the upcoming flu
season. Last year, it was reported that
in all pediatric age groups, LAIV did
not have any statistically significant
benefit in preventing influenza during
three flu seasons. Additional data on
LAIV4 are expected in October.
Also, Afluria (IIV3) now is indicated for people 5 years and older (down
from 9 years and older).
The CDC director will review
ACIP’s recommendations. Those that
are approved will be published as official recommendations in the
Morbidity and Mortality Weekly Report.
The Academy will review the CDC’s
changes and make official policy recommendations of its own.
Current CDC-AAP recommendations call for annual influenza vaccination for everyone 6 months of age
and older who doesn’t have contraindications.
During the current influenza sea-
son, 101 children have died, according
to reports to the CDC. Overall, flu
activity has been moderate, with peak
incidence in mid-February and re-
gional variation. Influenza A (H3N2)
viruses have predominated overall, but
since late March, influenza B viruses
have been reported more frequently
than A viruses.
Vaccine effectiveness for the current
season showed “significant protective-
ness” in children.
The U.S. influenza vaccine com-
position for the 2017-’ 18 season is as
• A/Michigan/45/2015 (H1N1)
pdm09-like virus (updated)
• A/Hong Kong/4801/2014 (H3N2)-
• B/Brisbane/60/2008-like virus (Vic-
• The three used in the trivalent vaccines, plus B/Phuket/3073/ 2013-
like virus (Yamagata lineage)
• Influenza chapter in Red Book Online,
• “Prevention and Control of Seasonal
Influenza with Vaccines: Recommen-
dations of the Advisory Committee
on Immunization Practices — Unit-
ed States, 2016–17 Influenza Sea-